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人類糖尿病,I型(少年,胰島素依賴型)qPCR檢測試劑盒

英文名:Human Diabetes, Type I (Juvenile, Insulin-dependent) qPCR Array Kit

貨號:GK050

價格:$250

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ScienCell's GeneQuery? Human Diabetes, Type I (Juvenile, Insulin-dependent) qPCR Array Kit (GQH-DB1) is designed to facilitate gene expression profiling of 88 key genes involved in the development and progression of insulin-dependent diabetes mellitus.  Type 1 diabetes mellitus is characterized by abnormally high blood sugar levels resultant of a disorder in glucose homeostasis.  Brief examples of how included genes may be grouped according to function are shown below:

  • Blood glucose regulation: INS, INSR, SLC2A2, SLC30A8, ABCC8
  • Autoimmunity: GAD1, GAD2, LTA, HLA-A, OAS1
  • Fat metabolism: ADIPOQ, LPL, PON1, LEP, RETN
  • Cholesterol regulation: APOA1, APOB, LPA, CETP, AMBP
  • Hormone regulation: PREP, IGF1, SST, HGF, REN

GeneQuery? qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis. 

GeneQuery? Human Diabetes, Type I (Juvenile, Insulin-dependent) qPCR Array Plate Layout* (8 controls in Bold and Italic) 

 

1

2

3

4

5

6

7

8

9

10

11

12

A

ABCC8

AKR1B1

CETP

GAD1

HLA-A

IAPP

IGFBP3

IRS1

NOS3

PTPRN

SLC2A4

β-actin

B

ACE

ALB

CLEC16A

GAD2

HLA-DQA1

ICA1

IL10

ITPR3

OAS1

PTPRN2

SLC30A8

GAPDH

C

ADIPOQ

AMBP

COG2

GCG

HLA-DQB1

IFIH1

IL1B

KCNJ11

PAX4

REN

SST

LDHA

D

ADRB3

AOC3

CPE

GCK

HLA-DRB1

IFNG

IL2RA

LEP

PDX1

RETN

SUMO4

NONO

E

AGER

APOA1

CRP

GH1

HNF1A

IGF1

IL4

LPA

PON1

SERPINE1

TG

PPIH

F

AGT

APOB

CTLA4

GHR

HNF1B

IGF2

IL6

LPL

PPARG

SH2D1A

TPO

GDC

G

AGTR1

CCR5

FOXP3

HBA2

HNF4A

IGFBP1

INS

LTA

PREP

SLC19A2

VDR

PPC

H

AIRE

CD79A

G6PC2

HGF

HSPD1

IGFBP2

INSR

NEUROD1

PTPN3

SLC2A2

WFS1

NT 

* gene selection may be updated based on new research and development

貨號GK050
產地美國
縮寫GQH-DB1
規格One 96-well plate, one 20ul reaction per well
用途科研
儲存4°C
運輸膠冰
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